GO WHERE NO SUTURE HAS GONE BEFORE

Unmet Need

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Mitral valve regurgitation (MR) is a backflow of blood that occurs when the heart’s mitral valve fails to close tightly - affecting roughly 2-3% of the global population.

But of the 7.8 million Americans who suffer from it, only around 70,000 opt for mitral repair or replacement surgeries annually due to their inherent high risk.  For everyone else, being forced to live with this potentially chronic condition.

A Transcatheter Breakthrough

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At ValSculpwe believe patients benefit the most of interventional procedures.  Our team specializes in developing advanced suturing systems, made specifically to be used via transcatheter, for the heart.

Our current focus is on a transcatheter technology called SATAR(Segmentally Adjustable Transcatheter Annuloplasty Ring) that aims to replicate and optimize the benefits of a surgical annuloplasty.

SATAR

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SATAR achieves this by delivering a ring composed of interconnected segments that can be inserted as a linear structure.  This design will allow adjustment of the annuloplasty ring configuration to optimize mitral valve leaflet coaptation.

The annuloplasty implant is secured with transcatheter sutures - thus providing outcomes comparable to surgical rings while avoiding invasive anchors. This transcatheter route also reduces and reshapes annulus dilatation to its native size and shape.

To this end, SATAR will not only be as efficient as semi-rigid surgical rings - but also have the ability to address both mitral and tricuspid valve regurgitations.

The Mitral Regurgitation Market

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176 million people affected worldwide

MR affects over 176 million people globally - 14 million in the US & Europe alone.  Here are are few more facts that reflect the outstanding opportunity we have with ValSculp

$3.0B by 2022

TMVR market expected to reach $3.0B by 2022 (15.9% CAGR from 2016-2022)

250,000

250,000 new patients suffer from MR each year

$250M-500M

Market acquisition activity is heating up, with top 5 companies acquiring MR treatment startups from $250M-500M and time-to-exit getting faster